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"Endometrial cancer is a disease mostly caused by excessive and prolonged stimulation of the endometrium -- the lining of the uterus -- by estrogens, unopposed by the hormone progesterone," Bandera said. "Obesity is associated with increased estrogen production by the adipose [fat] tissue in postmenopausal women, and is associated with increased insulin and insulin resistance as well as chronic inflammation. All of these factors affect the cells in the endometrium."

last-modified: 2021-03-20 23:37:54